CMap Candidate Details

Structure:
CMap ID: C25216
Pert ID: BRD-K71731651
Compound Name: PNU-120596
Targets: CHRNA7
MoA: Acetylcholine receptor agonist
SMILES: COc1cc(OC)c(NC(=O)Nc2cc(C)on2)cc1Cl
InchiKey: CEIIEALEIHQDBX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1614 BRD-K71731651 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1959 BRD-K71731651 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2197 BRD-K71731651 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2685 BRD-K71731651 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41834 BRD-K71731651 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42137 BRD-K71731651 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42457 BRD-K71731651 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42768 BRD-K71731651 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43065 BRD-K71731651 HT29 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.55
43230 BRD-K71731651 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43635 BRD-K71731651 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43934 BRD-K71731651 PHH 10 uM 24 h 0.27 1.13 0.28 0.0 0.0 0.0
44189 BRD-K71731651 SKB 10 uM 24 h 0.31 1.3 0.69 0.0 0.0 0.0
99422 BRD-K71731651 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.17 -0.59 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).