CMap Candidate Details

Structure:
CMap ID: C25262
Pert ID: BRD-K71847383
Compound Name: cytarabine
Targets: POLA1; POLB
MoA: Ribonucleotide reductase inhibitor
SMILES: Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
InchiKey: UHDGCWIWMRVCDJ-XVFCMESISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
115968 BRD-K71847383 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116006 BRD-K71847383 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116045 BRD-K71847383 HA1E 10 uM 24 h -0.31 -1.27 0.74 0.0 0.0 0.0
116087 BRD-K71847383 HCC515 10 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
116130 BRD-K71847383 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
116178 BRD-K71847383 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116217 BRD-K71847383 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.17
116257 BRD-K71847383 PC3 1.11 uM 24 h 0.17 0.7 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).