CMap Candidate Details

Structure:
CMap ID: C25273
Pert ID: BRD-K71879491
Compound Name: tretinoin
Targets: RARA; RARB; RARG; RORB
MoA: Retinoid receptor ligand; Retinoid receptor agonist
SMILES: CC(/C=C/C1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
InchiKey: SHGAZHPCJJPHSC-YCNIQYBTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
993 BRD-K71879491 CD34 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1052 BRD-K71879491 HL60 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1114 BRD-K71879491 U937 3.33 uM 6 h -0.27 -1.12 0.39 0.0 0.0 0.0
1131 BRD-K71879491 MCF??7.00 0.37 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1137 BRD-K71879491 PC3 2.22 uM 6 h 0.21 0.88 0.01 -0.31 -1.04 0.66
1449 BRD-K71879491 NPC 1.67 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34165 BRD-K71879491 ASC 10 uM 24 h -0.26 -1.08 0.3 0.3 1.07 0.63
36334 BRD-K71879491 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36631 BRD-K71879491 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36861 BRD-K71879491 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53325 BRD-K71879491 MCF10A 10 uM 24 h 0.22 0.91 0.04 0.0 0.0 0.0
90969 BRD-K71879491 HUH7 12 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99081 BRD-K71879491 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
111495 BRD-K71879491 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
115969 BRD-K71879491 A375 10 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
116008 BRD-K71879491 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116047 BRD-K71879491 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116090 BRD-K71879491 HCC515 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116134 BRD-K71879491 HEPG2 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116181 BRD-K71879491 HT29 0.37 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).