CMap Candidate Details

Structure:
CMap ID: C25286
Pert ID: BRD-K71935468
Compound Name: BRD-K71935468
Targets: --
MoA: --
SMILES: COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC
InchiKey: SIAMCPDTZJAYRI-XDWJUNQNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25629 BRD-K71935468 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25978 BRD-K71935468 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26440 BRD-K71935468 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26763 BRD-K71935468 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27065 BRD-K71935468 HCC515 10 uM 6 h 0.26 1.08 0.22 0.25 0.88 0.18
27376 BRD-K71935468 HT29 10 uM 6 h -0.16 -0.66 0.0 0.0 0.0 0.0
27742 BRD-K71935468 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
28009 BRD-K71935468 NEU 10 uM 24 h 0.23 0.96 0.08 -0.3 -1.0 0.55
28323 BRD-K71935468 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28516 BRD-K71935468 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28957 BRD-K71935468 PHH 10 uM 24 h 0.25 1.05 0.16 0.0 0.0 0.0
29291 BRD-K71935468 SKB 10 uM 24 h 0.28 1.18 0.39 -0.26 -0.89 0.26
29673 BRD-K71935468 VCAP 10 uM 6 h 0.22 0.92 0.04 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).