CMap Candidate Details

Structure:
CMap ID: C25310
Pert ID: BRD-K72024482
Compound Name: MRS-1754
Targets: ADORA2B
MoA: Adenosine receptor antagonist
SMILES: CCCn1c(=O)n(CCC)c2nc([nH]c2c1=O)c3ccc(OCC(=O)Nc4ccc(C#N)cc4)cc3
InchiKey: AJBBEYXFRYFVNM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1773 BRD-K72024482 HA1E 10 uM 6 h -0.22 -0.93 0.07 0.25 0.89 0.21
1961 BRD-K72024482 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2198 BRD-K72024482 PC3 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.53
2500 BRD-K72024482 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41976 BRD-K72024482 A549 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
42459 BRD-K72024482 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42770 BRD-K72024482 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43067 BRD-K72024482 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43351 BRD-K72024482 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43637 BRD-K72024482 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43936 BRD-K72024482 PHH 10 uM 24 h 0.28 1.17 0.36 0.0 0.0 0.0
44191 BRD-K72024482 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99426 BRD-K72024482 U2OS 10 uM 6 h -0.23 -0.98 0.12 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).