CMap Candidate Details

Structure:
CMap ID: C25366
Pert ID: BRD-K72215350
Compound Name: acexamic-acid
Targets: GAST
MoA: Reducing agent; Gastrin inhibitor; 5 alpha reductase inhibitor
SMILES: CC(=O)NCCCCCC(O)=O
InchiKey: WDSCBUNMANHPFH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126442 BRD-K72215350 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126478 BRD-K72215350 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
126579 BRD-K72215350 PC3 0.04 uM 24 h 0.23 0.97 0.08 -0.35 -1.17 1.14
126606 BRD-K72215350 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134350 BRD-K72215350 A375 0.25 uM 24 h -0.2 -0.83 0.0 -0.27 -0.91 0.31
134378 BRD-K72215350 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134401 BRD-K72215350 HA1E 0.25 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.31
134465 BRD-K72215350 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134508 BRD-K72215350 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134542 BRD-K72215350 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134569 BRD-K72215350 MCF??7.00 0.01 uM 24 h 0.29 1.22 0.47 0.0 0.0 0.0
134601 BRD-K72215350 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).