CMap Candidate Details

Structure:
CMap ID: C25374
Pert ID: BRD-K72238567
Compound Name: fludarabine
Targets: RRM1
MoA: DNA synthesis inhibitor
SMILES: Nc1nc(F)nc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
InchiKey: HBUBKKRHXORPQB-UUOKFMHZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25749 BRD-K72238567 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25979 BRD-K72238567 A549 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
26442 BRD-K72238567 ASC 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.43
26765 BRD-K72238567 HA1E 10 uM 6 h 0.0 0.0 0.0 0.36 1.27 1.33
27067 BRD-K72238567 HCC515 10 uM 6 h 0.0 0.0 0.0 0.42 1.5 2.26
27378 BRD-K72238567 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27743 BRD-K72238567 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
28011 BRD-K72238567 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28685 BRD-K72238567 PC3 10 uM 6 h 0.0 0.0 0.0 0.37 1.31 1.59
28959 BRD-K72238567 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29293 BRD-K72238567 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).