CMap Candidate Details
Structure:
CMap ID: | C25374 |
Pert ID: | BRD-K72238567 |
Compound Name: | fludarabine |
Targets: | RRM1 |
MoA: | DNA synthesis inhibitor |
SMILES: | Nc1nc(F)nc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O |
InchiKey: | HBUBKKRHXORPQB-UUOKFMHZSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
25749 | BRD-K72238567 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
25979 | BRD-K72238567 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.04 | 0.67 |
26442 | BRD-K72238567 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.0 | 0.43 |
26765 | BRD-K72238567 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.36 | 1.27 | 1.33 |
27067 | BRD-K72238567 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.42 | 1.5 | 2.26 |
27378 | BRD-K72238567 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
27743 | BRD-K72238567 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
28011 | BRD-K72238567 | NEU | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
28685 | BRD-K72238567 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.37 | 1.31 | 1.59 |
28959 | BRD-K72238567 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
29293 | BRD-K72238567 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |