CMap Candidate Details

Structure:
CMap ID: C25382
Pert ID: BRD-K72264770
Compound Name: QW-BI-011
Targets: EHMT2
MoA: Histone lysine methyltransferase inhibitor
SMILES: COC(=O)c1ccc2n(CCCc3ccccc3)c(NC(=O)c4ccccc4)nc2c1
InchiKey: UCGWYCMPZXDHNR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
26155 BRD-K72264770 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26443 BRD-K72264770 ASC 10 uM 24 h -0.21 -0.86 0.02 -0.34 -1.16 1.11
26766 BRD-K72264770 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.65
27068 BRD-K72264770 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27379 BRD-K72264770 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27600 BRD-K72264770 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
28012 BRD-K72264770 NEU 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
28325 BRD-K72264770 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28960 BRD-K72264770 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29294 BRD-K72264770 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29674 BRD-K72264770 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96729 BRD-K72264770 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96781 BRD-K72264770 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).