CMap Candidate Details

Structure:
CMap ID: C25441
Pert ID: BRD-K72462751
Compound Name: C-1
Targets: PRKCA
MoA: Protein kinase inhibitor
SMILES: O=S(=O)(N1CCNCC1)c1cccc2cnccc12
InchiKey: UPTYCYWTFGTCCG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4136 BRD-K72462751 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4476 BRD-K72462751 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39171 BRD-K72462751 A375 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.41
39485 BRD-K72462751 A549 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
39757 BRD-K72462751 ASC 10 uM 24 h 0.25 1.05 0.17 0.28 0.99 0.4
40050 BRD-K72462751 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40317 BRD-K72462751 HT29 10 uM 6 h -0.23 -0.95 0.09 0.0 0.0 0.0
40635 BRD-K72462751 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40859 BRD-K72462751 NEU 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
41175 BRD-K72462751 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
41513 BRD-K72462751 SKB 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
90376 BRD-K72462751 PC3 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
90419 BRD-K72462751 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99431 BRD-K72462751 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.19 -0.64 0.01
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).