CMap Candidate Details

Structure:
CMap ID: C25466
Pert ID: BRD-K72541103
Compound Name: BRD-K72541103
Targets: --
MoA: --
SMILES: OCc1cc2ncnc(Nc3ccc(O)cc3)c2cc1CO
InchiKey: OHQQFYCZENVXDJ-UHFFFAOYSA-N
Compound Aliases: JAK3-inhibitor-I

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1617 BRD-K72541103 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1963 BRD-K72541103 HCC515 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.34
2300 BRD-K72541103 PC3 10 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
41835 BRD-K72541103 A375 10 uM 6 h 0.27 1.11 0.26 0.28 1.0 0.42
41977 BRD-K72541103 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42461 BRD-K72541103 ASC 10 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
42772 BRD-K72541103 HEPG2 10 uM 6 h -0.21 -0.86 0.02 0.0 0.0 0.0
43068 BRD-K72541103 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43352 BRD-K72541103 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.25
43639 BRD-K72541103 NPC 10 uM 24 h -0.39 -1.62 15.35 -0.38 -1.29 1.53
43938 BRD-K72541103 PHH 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.09
44193 BRD-K72541103 SKB 10 uM 24 h -0.25 -1.03 0.19 0.0 0.0 0.0
90333 BRD-K72541103 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).