CMap Candidate Details

Structure:
CMap ID: C02548
Pert ID: BRD-K00486786
Compound Name: Ro-08-2750
Targets: NGF; NGFR
MoA: NGF binding inhibitor
SMILES: Cc1cc2nc3c(nc(=O)[nH]c3=O)n(C)c2cc1C=O
InchiKey: JDEMVNYMYPJJIM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1529 BRD-K00486786 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2067 BRD-K00486786 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.09
2282 BRD-K00486786 PC3 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
2764 BRD-K00486786 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41699 BRD-K00486786 A375 10 uM 6 h 0.17 0.69 0.0 0.0 0.0 0.0
41896 BRD-K00486786 A549 10 uM 24 h -0.22 -0.94 0.07 -0.31 -1.05 0.71
42257 BRD-K00486786 ASC 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
42593 BRD-K00486786 HEPG2 10 uM 6 h 0.24 1.0 0.1 0.0 0.0 0.0
42899 BRD-K00486786 HT29 10 uM 6 h 0.0 0.0 0.0 -0.43 -1.45 15.35
43144 BRD-K00486786 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43760 BRD-K00486786 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).