CMap Candidate Details

Structure:
CMap ID: C02549
Pert ID: BRD-K00494077
Compound Name: trovafloxacin
Targets: --
MoA: --
SMILES: N[C@H]1[C@@H]2CN(C[C@H]12)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F
InchiKey: WVPSKSLAZQPAKQ-CDMJZVDBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122845 BRD-K00494077 A549 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.03
122853 BRD-K00494077 HA1E 10 uM 24 h 0.27 1.11 0.25 -0.24 -0.82 0.15
122877 BRD-K00494077 HEK293 10 uM 24 h 0.29 1.2 0.43 0.0 0.0 0.0
122929 BRD-K00494077 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122961 BRD-K00494077 HT29 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.95
123002 BRD-K00494077 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123053 BRD-K00494077 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
123071 BRD-K00494077 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123091 BRD-K00494077 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123163 BRD-K00494077 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131200 BRD-K00494077 A375 2.22 uM 24 h 0.28 1.18 0.4 0.0 0.0 0.0
131339 BRD-K00494077 HUVEC 2.22 uM 24 h -0.18 -0.75 0.0 0.0 0.0 0.0
131452 BRD-K00494077 PC3 2.22 uM 24 h 0.26 1.07 0.2 0.0 0.0 0.0
131482 BRD-K00494077 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).