CMap Candidate Details

Structure:
CMap ID: C25497
Pert ID: BRD-K72676686
Compound Name: fluvoxamine
Targets: SLC6A4
MoA: Selective serotonin reuptake inhibitor
SMILES: COCCCCC(=NOCCN)c1ccc(cc1)C(F)(F)F
InchiKey: CJOFXWAVKWHTFT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4247 BRD-K72676686 HA1E 10 uM 6 h -0.23 -0.94 0.08 0.0 0.0 0.0
4477 BRD-K72676686 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
4958 BRD-K72676686 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39172 BRD-K72676686 A375 10 uM 6 h 0.0 0.0 0.0 0.35 1.22 1.15
39486 BRD-K72676686 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39758 BRD-K72676686 ASC 10 uM 24 h 0.0 0.0 0.0 0.35 1.24 1.27
40051 BRD-K72676686 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.32 1.15 0.88
40501 BRD-K72676686 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40860 BRD-K72676686 NEU 10 uM 24 h -0.23 -0.95 0.09 -0.31 -1.04 0.66
41176 BRD-K72676686 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41514 BRD-K72676686 SKB 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
52330 BRD-K72676686 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
114870 BRD-K72676686 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).