CMap Candidate Details

Structure:
CMap ID: C25553
Pert ID: BRD-K72816382
Compound Name: cinalukast
Targets: CYSLTR1
MoA: Leukotriene receptor antagonist
SMILES: CCC(CC)(CC(=O)Nc1cccc(C=Cc2nc(cs2)C3CCC3)c1)C(=O)O
InchiKey: BZMKNPGKXJAIDV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3048 BRD-K72816382 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3388 BRD-K72816382 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3537 BRD-K72816382 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3854 BRD-K72816382 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44436 BRD-K72816382 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44609 BRD-K72816382 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45306 BRD-K72816382 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.3
45567 BRD-K72816382 HT29 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.76
45714 BRD-K72816382 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46128 BRD-K72816382 NPC 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
46442 BRD-K72816382 PHH 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
46767 BRD-K72816382 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).