CMap Candidate Details
Structure:
| CMap ID: | C25566 |
| Pert ID: | BRD-K72853990 |
| Compound Name: | bromocriptine |
| Targets: | ADRA2A; ADRA2B; ADRA2C; DRD1; DRD2; DRD3; DRD4; DRD5; HTR1A; HTR1B; HTR1D; HTR2A; HTR2B; HTR2C |
| MoA: | Dopamine receptor agonist |
| SMILES: | CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@H]2CCCN2C1=O)C(C)C |
| InchiKey: | OZVBMTJYIDMWIL-JVOFPJAOSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 51322 | BRD-K72853990 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51504 | BRD-K72853990 | PC3 | 10 uM | 24 h | 0.19 | 0.81 | 0.0 | -0.39 | -1.32 | 1.71 |