CMap Candidate Details

Structure:
CMap ID: C25648
Pert ID: BRD-K73109821
Compound Name: diazoxide
Targets: KCNJ11
MoA: Potassium channel activator
SMILES: CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1
InchiKey: GDLBFKVLRPITMI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3255 BRD-K73109821 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25414 BRD-K73109821 VCAP 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.12
45015 BRD-K73109821 ASC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
45308 BRD-K73109821 HEPG2 10 uM 6 h -0.31 -1.29 0.77 0.0 0.0 0.0
46130 BRD-K73109821 NPC 10 uM 24 h 0.21 0.89 0.02 -0.25 -0.83 0.15
46444 BRD-K73109821 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46769 BRD-K73109821 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91104 BRD-K73109821 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99440 BRD-K73109821 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
126661 BRD-K73109821 A549 10 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.06
126682 BRD-K73109821 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126731 BRD-K73109821 HELA 10 uM 24 h 0.24 1.02 0.13 0.0 0.0 0.0
126756 BRD-K73109821 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.12
126863 BRD-K73109821 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126905 BRD-K73109821 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126978 BRD-K73109821 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134688 BRD-K73109821 A375 0.74 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
134782 BRD-K73109821 HEK293 0.03 uM 24 h 0.29 1.22 0.48 -0.35 -1.19 1.16
134892 BRD-K73109821 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134914 BRD-K73109821 JURKAT 0.01 uM 24 h -0.26 -1.09 0.32 0.0 0.0 0.0
134936 BRD-K73109821 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134978 BRD-K73109821 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135008 BRD-K73109821 YAPC 0.01 uM 24 h 0.21 0.87 0.01 -0.27 -0.9 0.29
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).