CMap Candidate Details

Structure:
CMap ID: C25693
Pert ID: BRD-K73237276
Compound Name: tacalcitol
Targets: VDR
MoA: Vitamin D receptor agonist
SMILES: CC(C)[C@H](O)CC[C@@H](C)[C@H]1CC[C@@H]2[C@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C
InchiKey: BJYLYJCXYAMOFT-RSFVBTMBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95308 BRD-K73237276 A549 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
95466 BRD-K73237276 U2OS 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
126446 BRD-K73237276 HEK293 0.04 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
126497 BRD-K73237276 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126524 BRD-K73237276 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.45
126581 BRD-K73237276 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126608 BRD-K73237276 YAPC 0.37 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
134354 BRD-K73237276 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134405 BRD-K73237276 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134434 BRD-K73237276 HELA 0.08 uM 24 h 0.25 1.06 0.19 0.0 0.0 0.0
134513 BRD-K73237276 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 -0.41 -1.39 2.02
134571 BRD-K73237276 MCF??7.00 0.74 uM 24 h -0.28 -1.18 0.51 -0.3 -1.01 0.58
134605 BRD-K73237276 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.36
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).