CMap Candidate Details

Structure:
CMap ID: C25711
Pert ID: BRD-K73290745
Compound Name: ICI-199441
Targets: OPRK1
MoA: Opioid receptor agonist
SMILES: CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(Cl)c(Cl)c1
InchiKey: AEJOEPSMZCEYJN-HXUWFJFHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4249 BRD-K73290745 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4479 BRD-K73290745 HCC515 10 uM 24 h -0.19 -0.78 0.0 0.35 1.23 1.19
4717 BRD-K73290745 PC3 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.72
5122 BRD-K73290745 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44438 BRD-K73290745 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44610 BRD-K73290745 A549 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
45016 BRD-K73290745 ASC 10 uM 24 h -0.17 -0.7 0.0 0.0 0.0 0.0
45309 BRD-K73290745 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45569 BRD-K73290745 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45716 BRD-K73290745 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46131 BRD-K73290745 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46445 BRD-K73290745 PHH 10 uM 24 h 0.29 1.22 0.48 -0.25 -0.84 0.18
46770 BRD-K73290745 SKB 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
99444 BRD-K73290745 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).