CMap Candidate Details

Structure:
CMap ID: C25857
Pert ID: BRD-K73691377
Compound Name: alprostadil
Targets: PTGER1; PTGER2
MoA: Prostanoid receptor agonist
SMILES: CCCCC[C@H](O)C=C[C@@H]1[C@@H](O)CC(=O)[C@H]1CCCCCCC(O)=O
InchiKey: GMVPRGQOIOIIMI-AIJKCLAYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121794 BRD-K73691377 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121842 BRD-K73691377 PC3 1.11 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
129756 BRD-K73691377 A375 0.03 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.94
129792 BRD-K73691377 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129827 BRD-K73691377 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129872 BRD-K73691377 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129916 BRD-K73691377 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
129954 BRD-K73691377 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 -0.21 -0.7 0.03
129998 BRD-K73691377 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130038 BRD-K73691377 MDAMB231 0.03 uM 24 h -0.19 -0.8 0.0 0.0 0.0 0.0
130110 BRD-K73691377 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130157 BRD-K73691377 YAPC 0.03 uM 24 h -0.34 -1.41 1.26 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).