CMap Candidate Details

Structure:
CMap ID: C25884
Pert ID: BRD-K73794685
Compound Name: azithromycin
Targets: --
MoA: --
SMILES: CC[C@H]1OC(=O)[C@@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O
InchiKey: MQTOSJVFKKJCRP-MTXCBGCVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127063 BRD-K73794685 HEK293 10 uM 24 h -0.25 -1.06 0.25 0.0 0.0 0.0
127087 BRD-K73794685 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127177 BRD-K73794685 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127226 BRD-K73794685 PC3 1.11 uM 24 h 0.33 1.37 0.97 0.0 0.0 0.0
127267 BRD-K73794685 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
135010 BRD-K73794685 A375 0.08 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
135029 BRD-K73794685 A549 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135073 BRD-K73794685 HA1E 0.08 uM 24 h 0.24 1.0 0.1 0.26 0.91 0.23
135140 BRD-K73794685 HT29 0.08 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
135161 BRD-K73794685 JURKAT 0.25 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
135225 BRD-K73794685 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
135246 BRD-K73794685 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135318 BRD-K73794685 YAPC 0.08 uM 24 h 0.22 0.93 0.05 0.35 1.25 1.29
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).