CMap Candidate Details

Structure:
CMap ID: C25891
Pert ID: BRD-K73815512
Compound Name: HC-030031
Targets: TRPA1
MoA: TRPA1 channel blocker
SMILES: CC(C)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1
InchiKey: HEQDZPHDVAOBLN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127352 BRD-K73815512 A375 10 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
127392 BRD-K73815512 A549 0.04 uM 24 h -0.24 -1.0 0.14 0.0 0.0 0.0
127424 BRD-K73815512 HA1E 0.37 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
127515 BRD-K73815512 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.45
127574 BRD-K73815512 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127607 BRD-K73815512 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127646 BRD-K73815512 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127685 BRD-K73815512 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135369 BRD-K73815512 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135402 BRD-K73815512 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135439 BRD-K73815512 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).