CMap Candidate Details

Structure:
CMap ID: C25894
Pert ID: BRD-K73824630
Compound Name: skatole
Targets: CYP2F1
MoA: Thrombin inhibitor
SMILES: Cc1c[nH]c2ccccc12
InchiKey: ZFRKQXVRDFCRJG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3049 BRD-K73824630 HA1E 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.34
3390 BRD-K73824630 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.66
3538 BRD-K73824630 PC3 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
3856 BRD-K73824630 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44440 BRD-K73824630 A375 10 uM 6 h 0.24 1.0 0.1 -0.3 -1.02 0.61
44613 BRD-K73824630 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45019 BRD-K73824630 ASC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
45312 BRD-K73824630 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45572 BRD-K73824630 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45844 BRD-K73824630 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46134 BRD-K73824630 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46448 BRD-K73824630 PHH 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
46773 BRD-K73824630 SKB 10 uM 24 h 0.24 0.99 0.1 0.37 1.32 1.62
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).