CMap Candidate Details

Structure:
CMap ID: C00259
Pert ID: BRD-A10039652
Compound Name: tipranavir
Targets: --
MoA: --
SMILES: CCC[C@@]1(CCc2ccccc2)CC(=O)C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c2)C(=O)O1
InchiKey: MYXACKZCYFKMTE-JETRDCLMSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121157 BRD-A10039652 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121194 BRD-A10039652 A549 0.37 uM 24 h 0.24 1.0 0.1 -0.25 -0.83 0.17
121227 BRD-A10039652 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121323 BRD-A10039652 PC3 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.87
129278 BRD-A10039652 HELA 0.74 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129306 BRD-A10039652 HT29 2.22 uM 24 h -0.3 -1.23 0.64 -0.24 -0.79 0.11
129341 BRD-A10039652 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
129378 BRD-A10039652 YAPC 0.03 uM 24 h 0.21 0.89 0.02 0.2 0.71 0.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).