CMap Candidate Details

Structure:
CMap ID: C25941
Pert ID: BRD-K73978287
Compound Name: hydrocortisone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@]1(O)C(=O)COC(=O)CCC(=O)O
InchiKey: VWQWXZAWFPZJDA-VDINROJTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49884 BRD-K73978287 A375 10 uM 6 h 0.21 0.88 0.02 0.0 0.0 0.0
50048 BRD-K73978287 A549 10 uM 6 h -0.21 -0.89 0.03 0.3 1.07 0.62
50231 BRD-K73978287 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50406 BRD-K73978287 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50579 BRD-K73978287 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50778 BRD-K73978287 MCF??7.00 10 uM 6 h -0.29 -1.22 0.61 0.25 0.88 0.18
50860 BRD-K73978287 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51176 BRD-K73978287 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).