CMap Candidate Details
Structure:
CMap ID: | C25941 |
Pert ID: | BRD-K73978287 |
Compound Name: | hydrocortisone |
Targets: | NR3C1 |
MoA: | Glucocorticoid receptor agonist |
SMILES: | C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@]1(O)C(=O)COC(=O)CCC(=O)O |
InchiKey: | VWQWXZAWFPZJDA-VDINROJTSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
49884 | BRD-K73978287 | A375 | 10 uM | 6 h | 0.21 | 0.88 | 0.02 | 0.0 | 0.0 | 0.0 |
50048 | BRD-K73978287 | A549 | 10 uM | 6 h | -0.21 | -0.89 | 0.03 | 0.3 | 1.07 | 0.62 |
50231 | BRD-K73978287 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
50406 | BRD-K73978287 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
50579 | BRD-K73978287 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
50778 | BRD-K73978287 | MCF??7.00 | 10 uM | 6 h | -0.29 | -1.22 | 0.61 | 0.25 | 0.88 | 0.18 |
50860 | BRD-K73978287 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
51176 | BRD-K73978287 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |