CMap Candidate Details

Structure:
CMap ID: C25943
Pert ID: BRD-K73991644
Compound Name: isoquercetin
Targets: AKR1B1
MoA: Aldose reductase inhibitor
SMILES: OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O
InchiKey: OVSQVDMCBVZWGM-QSOFNFLRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24476 BRD-K73991644 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24606 BRD-K73991644 A549 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
24805 BRD-K73991644 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24942 BRD-K73991644 HT29 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.46
25185 BRD-K73991644 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25416 BRD-K73991644 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99451 BRD-K73991644 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).