CMap Candidate Details

Structure:
CMap ID: C25947
Pert ID: BRD-K73999723
Compound Name: telmisartan
Targets: AGTR1; PPARG
MoA: Angiotensin receptor antagonist
SMILES: CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1nc2ccccc2n1C
InchiKey: RMMXLENWKUUMAY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4481 BRD-K73999723 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
25534 BRD-K73999723 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
40053 BRD-K73999723 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41178 BRD-K73999723 NPC 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.68
41516 BRD-K73999723 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91492 BRD-K73999723 HUH7 6.66 uM 72 h 0.21 0.87 0.01 0.22 0.79 0.07
95304 BRD-K73999723 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
95460 BRD-K73999723 U2OS 1.11 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.22
97124 BRD-K73999723 A375 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
97192 BRD-K73999723 PC3 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.42
127428 BRD-K73999723 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
127467 BRD-K73999723 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127519 BRD-K73999723 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127576 BRD-K73999723 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127689 BRD-K73999723 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135406 BRD-K73999723 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
135440 BRD-K73999723 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.47
135500 BRD-K73999723 THP1 2.22 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.94
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).