CMap Candidate Details

Structure:
CMap ID: C02598
Pert ID: BRD-K00610438
Compound Name: altanserin
Targets: HTR2A
MoA: Serotonin receptor antagonist
SMILES: Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=S)[nH]c3ccccc3c2=O)CC1
InchiKey: SMYALUSCZJXWHG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4330 BRD-K00610438 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25315 BRD-K00610438 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44807 BRD-K00610438 ASC 10 uM 24 h -0.3 -1.24 0.67 -0.34 -1.16 1.1
45123 BRD-K00610438 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45925 BRD-K00610438 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46244 BRD-K00610438 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46558 BRD-K00610438 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122829 BRD-K00610438 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122879 BRD-K00610438 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122931 BRD-K00610438 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
122963 BRD-K00610438 HT29 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
123004 BRD-K00610438 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123093 BRD-K00610438 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123165 BRD-K00610438 THP1 3.33 uM 24 h -0.23 -0.98 0.12 -0.27 -0.91 0.31
131230 BRD-K00610438 A549 0.03 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.39
131270 BRD-K00610438 HA1E 0.03 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.05
131341 BRD-K00610438 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131391 BRD-K00610438 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
131425 BRD-K00610438 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131454 BRD-K00610438 PC3 2.22 uM 24 h -0.23 -0.98 0.12 0.0 0.0 0.0
131484 BRD-K00610438 YAPC 2.22 uM 24 h 0.31 1.28 0.63 -0.27 -0.9 0.29
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).