CMap Candidate Details

Structure:
CMap ID: C00026
Pert ID: BRD-A00993607
Compound Name: alprenolol
Targets: ADRB1; ADRB2
MoA: Adrenergic receptor antagonist
SMILES: CC(C)NCC(O)COc1ccccc1CC=C
InchiKey: PAZJSJFMUHDSTF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5244 BRD-A00993607 HA1E 10 uM 24 h -0.19 -0.77 0.0 0.0 0.0 0.0
5484 BRD-A00993607 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6118 BRD-A00993607 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6442 BRD-A00993607 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39029 BRD-A00993607 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39258 BRD-A00993607 A549 10 uM 24 h 0.17 0.7 0.0 0.0 0.0 0.0
39543 BRD-A00993607 ASC 10 uM 24 h 0.29 1.2 0.42 0.0 0.0 0.0
39875 BRD-A00993607 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40160 BRD-A00993607 HT29 10 uM 6 h 0.0 0.0 0.0 0.31 1.08 0.66
40676 BRD-A00993607 NEU 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.53
40969 BRD-A00993607 NPC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
41293 BRD-A00993607 SKB 10 uM 24 h 0.18 0.77 0.0 0.0 0.0 0.0
51265 BRD-A00993607 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91010 BRD-A00993607 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).