CMap Candidate Details

Structure:
CMap ID: C00260
Pert ID: BRD-A10070317
Compound Name: propranolol
Targets: ADRB2; ADRB3
MoA: Adrenergic receptor antagonist
SMILES: CC(C)NCC(O)COc1cccc2ccccc12
InchiKey: AQHHHDLHHXJYJD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
20180 BRD-A10070317 HEPG2 10 uM 6 h 0.22 0.93 0.05 -0.26 -0.87 0.22
20517 BRD-A10070317 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21673 BRD-A10070317 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91421 BRD-A10070317 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
96005 BRD-A10070317 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121159 BRD-A10070317 A375 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.11
121196 BRD-A10070317 A549 3.33 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
121229 BRD-A10070317 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121270 BRD-A10070317 HELA 0.37 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129343 BRD-A10070317 MCF??7.00 0.08 uM 24 h 0.25 1.03 0.13 0.19 0.67 0.01
129356 BRD-A10070317 PC3 2.22 uM 24 h 0.24 1.02 0.13 0.28 1.0 0.42
129381 BRD-A10070317 YAPC 0.01 uM 24 h 0.22 0.93 0.05 -0.32 -1.07 0.76
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).