CMap Candidate Details

Structure:
CMap ID: C26025
Pert ID: BRD-K74236984
Compound Name: UNC-0321
Targets: EHMT2
MoA: Histone lysine methyltransferase inhibitor
SMILES: COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1OCCOCCN(C)C)N1CCCN(C)CC1
InchiKey: AULLUGALUBVBDD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8978 BRD-K74236984 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9116 BRD-K74236984 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9881 BRD-K74236984 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
10124 BRD-K74236984 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10586 BRD-K74236984 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10843 BRD-K74236984 HEPG2 10 uM 6 h 0.2 0.84 0.0 0.0 0.0 0.0
11011 BRD-K74236984 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11139 BRD-K74236984 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.38 1.33 1.72
11567 BRD-K74236984 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12124 BRD-K74236984 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12940 BRD-K74236984 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13351 BRD-K74236984 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13674 BRD-K74236984 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95748 BRD-K74236984 NPC 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.16
95933 BRD-K74236984 YAPC 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.23 1.28
96806 BRD-K74236984 PC3 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).