CMap Candidate Details

Structure:
CMap ID: C26048
Pert ID: BRD-K74305673
Compound Name: BRD-K74305673
Targets: --
MoA: --
SMILES: Oc1ccc(Cl)cc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
InchiKey: CHILCFMQWMQVAL-UHFFFAOYSA-N
Compound Aliases: IKK-2-inhibitor-V

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1774 BRD-K74305673 HA1E 10 uM 6 h -0.29 -1.2 0.57 0.25 0.88 0.19
2120 BRD-K74305673 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.22
2608 BRD-K74305673 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9117 BRD-K74305673 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9500 BRD-K74305673 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9804 BRD-K74305673 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10587 BRD-K74305673 HCT116 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.12 0.95
11568 BRD-K74305673 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.48 -1.63 15.65
11831 BRD-K74305673 NCIH508 10 uM 6 h 0.25 1.04 0.15 0.0 0.0 0.0
12125 BRD-K74305673 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.43 -1.46 15.35
12861 BRD-K74305673 SW480 10 uM 6 h -0.29 -1.2 0.56 0.0 0.0 0.0
13352 BRD-K74305673 U937 10 uM 6 h 0.0 0.0 0.0 0.33 1.18 0.97
45020 BRD-K74305673 ASC 10 uM 24 h 0.28 1.15 0.33 0.0 0.0 0.0
46449 BRD-K74305673 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46774 BRD-K74305673 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53411 BRD-K74305673 HEPG2 10 uM 24 h -0.13 -0.54 0.0 -0.25 -0.83 0.15
53607 BRD-K74305673 HUH7 10 uM 6 h -0.21 -0.85 0.01 0.0 0.0 0.0
97261 BRD-K74305673 HAP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99457 BRD-K74305673 U2OS 10 uM 6 h 0.2 0.83 0.0 -0.33 -1.12 0.94
127010 BRD-K74305673 A375 0.125 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
127090 BRD-K74305673 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.33
127158 BRD-K74305673 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127201 BRD-K74305673 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
127228 BRD-K74305673 PC3 0.125 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
127270 BRD-K74305673 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135096 BRD-K74305673 HEK293 0.74 uM 24 h -0.24 -1.01 0.16 0.24 0.86 0.16
135141 BRD-K74305673 HT29 2.22 uM 24 h -0.24 -1.02 0.17 0.0 0.0 0.0
135196 BRD-K74305673 MCF10A 2.22 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
135249 BRD-K74305673 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.31
135320 BRD-K74305673 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.38 1.35 1.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).