CMap Candidate Details

Structure:
CMap ID: C02605
Pert ID: BRD-K00627859
Compound Name: tubastatin-a
Targets: HDAC6
MoA: HDAC inhibitor
SMILES: CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO
InchiKey: GOVYBPLHWIEHEJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
46837 BRD-K00627859 A375 10 uM 6 h 0.0 0.0 0.0 0.26 0.93 0.27
47164 BRD-K00627859 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
48478 BRD-K00627859 HT29 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
49607 BRD-K00627859 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119227 BRD-K00627859 HA1E 10 uM 24 h 0.18 0.74 0.0 -0.26 -0.86 0.22
119256 BRD-K00627859 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.03 0.62
119287 BRD-K00627859 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.29
119341 BRD-K00627859 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119365 BRD-K00627859 PC3 10 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).