CMap Candidate Details

Structure:
CMap ID: C26060
Pert ID: BRD-K74339692
Compound Name: tamsulosin
Targets: ADRA1D; ADRA1B; ADRA1A
MoA: Adrenergic receptor antagonist
SMILES: CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(c1)S(N)(=O)=O
InchiKey: DRHKJLXJIQTDTD-OAHLLOKOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91490 BRD-K74339692 HUH7 8 uM 72 h 0.22 0.93 0.05 0.0 0.0 0.0
127039 BRD-K74339692 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127160 BRD-K74339692 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127203 BRD-K74339692 MCF??7.00 0.37 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
127230 BRD-K74339692 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127273 BRD-K74339692 THP1 3.33 uM 24 h 0.25 1.06 0.19 -0.3 -1.0 0.54
127306 BRD-K74339692 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135013 BRD-K74339692 A375 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135033 BRD-K74339692 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135099 BRD-K74339692 HEK293 0.08 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
135126 BRD-K74339692 HELA 0.25 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
135144 BRD-K74339692 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135198 BRD-K74339692 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135252 BRD-K74339692 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).