CMap Candidate Details

Structure:
CMap ID: C26074
Pert ID: BRD-K74402642
Compound Name: NSC-632839
Targets: SENP2; USP1; USP7; USP2
MoA: Ubiquitin specific protease inhibitor
SMILES: Cc1ccc(/C=C/2CNC/C(=C/c3ccc(C)cc3)/C2=O)cc1
InchiKey: PKCYYPHSCUSQDK-UHWBUFEVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8979 BRD-K74402642 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9501 BRD-K74402642 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9805 BRD-K74402642 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10079 BRD-K74402642 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10189 BRD-K74402642 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.33
10588 BRD-K74402642 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10844 BRD-K74402642 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.43 -1.43 15.35
11090 BRD-K74402642 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11296 BRD-K74402642 MCF??7.00 10 uM 6 h 0.31 1.28 0.61 0.0 0.0 0.0
11569 BRD-K74402642 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.29 1.51
11832 BRD-K74402642 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12126 BRD-K74402642 NCIH596 10 uM 6 h 0.3 1.23 0.5 -0.33 -1.12 0.94
12376 BRD-K74402642 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12626 BRD-K74402642 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12862 BRD-K74402642 SW480 10 uM 6 h 0.0 0.0 0.0 -0.44 -1.47 15.35
13031 BRD-K74402642 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13353 BRD-K74402642 U937 10 uM 6 h 0.21 0.88 0.01 0.0 0.0 0.0
13675 BRD-K74402642 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.36 2.02
90532 BRD-K74402642 A549 3.33 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).