CMap Candidate Details

Structure:
CMap ID: C26137
Pert ID: BRD-K74623475
Compound Name: BRD-K74623475
Targets: --
MoA: --
SMILES: COc1ccc(CN(C)C[C@@H]2OCCCC[C@H](C)Oc3ccc(NC(=O)Nc4ccc(cc4)C(F)(F)F)cc3C(=O)N(C[C@H]2C)[C@H](C)CO)cc1
InchiKey: XGMQKVJTWVADHD-NUNJUMJCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29940 BRD-K74623475 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30108 BRD-K74623475 A549 10 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
30545 BRD-K74623475 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30837 BRD-K74623475 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31128 BRD-K74623475 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31441 BRD-K74623475 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.72 0.04
31745 BRD-K74623475 HT29 10 uM 6 h -0.2 -0.81 0.0 0.0 0.0 0.0
32069 BRD-K74623475 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.32
32231 BRD-K74623475 NEU 10 uM 24 h -0.24 -0.99 0.14 0.25 0.9 0.22
32520 BRD-K74623475 NPC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
32827 BRD-K74623475 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33129 BRD-K74623475 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33349 BRD-K74623475 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).