CMap Candidate Details

Structure:
CMap ID: C02614
Pert ID: BRD-K00662280
Compound Name: CL-218872
Targets: GABRA1
MoA: GABA receptor agonist
SMILES: Cc1nnc2ccc(nn12)-c1cccc(c1)C(F)(F)F
InchiKey: GUOQUXNJZHGPQF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2826 BRD-K00662280 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.18 -0.61 0.0
3127 BRD-K00662280 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3459 BRD-K00662280 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3712 BRD-K00662280 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39616 BRD-K00662280 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39936 BRD-K00662280 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40741 BRD-K00662280 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41366 BRD-K00662280 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99949 BRD-K00662280 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
122882 BRD-K00662280 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123007 BRD-K00662280 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123055 BRD-K00662280 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123072 BRD-K00662280 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
123096 BRD-K00662280 MDAMB231 3.33 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
123168 BRD-K00662280 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123213 BRD-K00662280 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131201 BRD-K00662280 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131233 BRD-K00662280 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131298 BRD-K00662280 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131323 BRD-K00662280 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
131344 BRD-K00662280 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).