CMap Candidate Details
Structure:
| CMap ID: | C26198 |
| Pert ID: | BRD-K74793820 |
| Compound Name: | vincristine |
| Targets: | TUBB |
| MoA: | Tubulin inhibitor |
| SMILES: | CC[C@]1(O)C[C@H]2C[N@@](C1)CCc1c([nH]c3ccccc13)[C@@](C2)(C(=O)OC)c1cc2c(cc1OC)N(C=O)[C@@H]1[C@]22CCN3CC=C[C@@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC |
| InchiKey: | OGWKCGZFUXNPDA-YPKBQUEXSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 52418 | BRD-K74793820 | HA1E | 10 uM | 6 h | 0.24 | 1.0 | 0.11 | 0.0 | 0.0 | 0.0 |
| 52462 | BRD-K74793820 | PC3 | 10 uM | 24 h | -0.26 | -1.07 | 0.27 | -0.27 | -0.92 | 0.32 |