CMap Candidate Details

Structure:
CMap ID: C00262
Pert ID: BRD-A10188456
Compound Name: dexamethasone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InchiKey: UREBDLICKHMUKA-QCYOSJOCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5145 BRD-A10188456 A375 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.86
5252 BRD-A10188456 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 1.0
5495 BRD-A10188456 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
6062 BRD-A10188456 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.26 0.91 0.23
6122 BRD-A10188456 PC3 10 uM 24 h 0.14 0.59 0.0 0.26 0.91 0.23
6345 BRD-A10188456 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41867 BRD-A10188456 A549 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.95
42171 BRD-A10188456 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42516 BRD-A10188456 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42827 BRD-A10188456 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43374 BRD-A10188456 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43689 BRD-A10188456 PHH 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
43987 BRD-A10188456 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).