CMap Candidate Details

Structure:
CMap ID: C02621
Pert ID: BRD-K00673382
Compound Name: famotidine
Targets: HRH2
MoA: Histamine receptor antagonist
SMILES: NC(N)=Nc1nc(CSCCC(N)=N/S(N)(=O)=O)cs1
InchiKey: XUFQPHANEAPEMJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25316 BRD-K00673382 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51293 BRD-K00673382 MCF??7.00 10 uM 6 h -0.18 -0.76 0.0 0.0 0.0 0.0
91054 BRD-K00673382 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99950 BRD-K00673382 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
122883 BRD-K00673382 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122964 BRD-K00673382 HT29 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
123008 BRD-K00673382 JURKAT 1.11 uM 24 h -0.22 -0.91 0.05 -0.22 -0.75 0.07
123056 BRD-K00673382 MCF10A 0.04 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
123097 BRD-K00673382 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123143 BRD-K00673382 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
123169 BRD-K00673382 THP1 0.04 uM 24 h -0.34 -1.42 1.42 -0.29 -0.99 0.5
131202 BRD-K00673382 A375 0.74 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
131234 BRD-K00673382 A549 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131273 BRD-K00673382 HA1E 0.74 uM 24 h 0.31 1.3 0.73 0.0 0.0 0.0
131299 BRD-K00673382 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131345 BRD-K00673382 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.82
131486 BRD-K00673382 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).