CMap Candidate Details

Structure:
CMap ID: C02623
Pert ID: BRD-K00675675
Compound Name: CL-82198
Targets: MMP13
MoA: Metalloproteinase inhibitor
SMILES: O=C(NCCCCN1CCOCC1)c2cc3ccccc3o2
InchiKey: KUJQEQAVMNFFAO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4035 BRD-K00675675 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4535 BRD-K00675675 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.47
4873 BRD-K00675675 VCAP 10 uM 24 h 0.22 0.92 0.04 -0.4 -1.35 1.88
44503 BRD-K00675675 A549 10 uM 24 h -0.18 -0.75 0.0 0.29 1.03 0.5
44808 BRD-K00675675 ASC 10 uM 24 h 0.0 0.0 0.0 0.34 1.19 1.04
45124 BRD-K00675675 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45396 BRD-K00675675 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45631 BRD-K00675675 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.39 2.02
45926 BRD-K00675675 NPC 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
46245 BRD-K00675675 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46559 BRD-K00675675 SKB 10 uM 24 h 0.21 0.87 0.01 -0.22 -0.75 0.07
96870 BRD-K00675675 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.08
96944 BRD-K00675675 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
99951 BRD-K00675675 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).