CMap Candidate Details

Structure:
CMap ID: C26249
Pert ID: BRD-K74931283
Compound Name: BRD-K74931283
Targets: --
MoA: --
SMILES: C[C@@H](CO)N1C[C@H](C)[C@@H](CN(C)Cc2ccc(Cl)c(Cl)c2)Oc3c(NC(=O)Nc4ccc(F)cc4)cccc3C1=O
InchiKey: VLUBEHZZNKTZLC-RWYJCYHVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29941 BRD-K74931283 A375 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.84
30244 BRD-K74931283 A549 10 uM 6 h 0.26 1.09 0.23 -0.26 -0.89 0.27
30546 BRD-K74931283 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30838 BRD-K74931283 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31129 BRD-K74931283 HCC515 10 uM 6 h 0.24 0.99 0.1 0.0 0.0 0.0
31442 BRD-K74931283 HEPG2 10 uM 6 h -0.29 -1.21 0.57 0.22 0.77 0.05
31536 BRD-K74931283 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
32070 BRD-K74931283 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.31 1.69
32232 BRD-K74931283 NEU 10 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.76
32521 BRD-K74931283 NPC 10 uM 24 h -0.26 -1.09 0.32 -0.32 -1.07 0.78
32828 BRD-K74931283 PC3 10 uM 6 h 0.0 0.0 0.0 -0.43 -1.44 15.35
33130 BRD-K74931283 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33350 BRD-K74931283 VCAP 10 uM 24 h 0.22 0.91 0.03 -0.33 -1.12 0.93
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).