CMap Candidate Details

Structure:
CMap ID: C26252
Pert ID: BRD-K74949371
Compound Name: BRD-K74949371
Targets: --
MoA: --
SMILES: C[C@H](CO)N1C[C@H](C)[C@H](CN(C)C(=O)Nc2ccc(cc2)C(F)(F)F)Oc3c(NC(=O)c4ccc(cc4)c5nccs5)cccc3C1=O
InchiKey: PRPSIXOCSCMWNX-GTNJKRJXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29942 BRD-K74949371 A375 10 uM 6 h 0.0 0.0 0.0 0.25 0.9 0.21
30245 BRD-K74949371 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30547 BRD-K74949371 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
31130 BRD-K74949371 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31443 BRD-K74949371 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31783 BRD-K74949371 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31923 BRD-K74949371 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32233 BRD-K74949371 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32522 BRD-K74949371 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32675 BRD-K74949371 PC3 10 uM 24 h -0.25 -1.03 0.2 0.0 0.0 0.0
33131 BRD-K74949371 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33351 BRD-K74949371 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).