CMap Candidate Details

Structure:
CMap ID: C26281
Pert ID: BRD-K75037734
Compound Name: carbachol
Targets: CHRM1; CHRM2; CHRNA2
MoA: Cholinergic receptor agonist
SMILES: C[N+](C)(C)CCOC(N)=O
InchiKey: VPJXQGSRWJZDOB-UHFFFAOYSA-O
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91048 BRD-K75037734 HUH7 25 uM 72 h 0.0 0.0 0.0 0.25 0.89 0.2
127014 BRD-K75037734 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127133 BRD-K75037734 HT29 0.04 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
127180 BRD-K75037734 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.42
127233 BRD-K75037734 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127275 BRD-K75037734 THP1 1.11 uM 24 h 0.17 0.71 0.0 0.27 0.95 0.31
135037 BRD-K75037734 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135079 BRD-K75037734 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.17
135103 BRD-K75037734 HEK293 0.25 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
135128 BRD-K75037734 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135167 BRD-K75037734 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
135227 BRD-K75037734 MCF??7.00 0.74 uM 24 h 0.23 0.94 0.06 0.31 1.1 0.69
135256 BRD-K75037734 MDAMB231 0.03 uM 24 h 0.36 1.51 1.43 0.2 0.72 0.02
135324 BRD-K75037734 YAPC 0.25 uM 24 h -0.2 -0.82 0.0 -0.27 -0.91 0.31
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).