CMap Candidate Details

Structure:
CMap ID: C26299
Pert ID: BRD-K75089421
Compound Name: procainamide
Targets: SCN5A
MoA: Sodium channel blocker
SMILES: CCN(CC)CCNC(=O)c1ccc(N)cc1
InchiKey: REQCZEXYDRLIBE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4483 BRD-K75089421 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37732 BRD-K75089421 ASC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.12
38549 BRD-K75089421 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
38773 BRD-K75089421 PHH 10 uM 24 h 0.23 0.97 0.08 0.25 0.89 0.2
51178 BRD-K75089421 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90983 BRD-K75089421 HUH7 15 uM 72 h 0.0 0.0 0.0 -0.24 -0.82 0.15
127016 BRD-K75089421 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127095 BRD-K75089421 HELA 0.04 uM 24 h 0.0 0.0 0.0 -0.19 -0.63 0.0
127136 BRD-K75089421 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127163 BRD-K75089421 JURKAT 0.37 uM 24 h -0.22 -0.91 0.06 -0.43 -1.45 15.35
127206 BRD-K75089421 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127235 BRD-K75089421 PC3 0.125 uM 24 h -0.2 -0.83 0.0 -0.25 -0.85 0.19
127278 BRD-K75089421 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.43
127309 BRD-K75089421 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135040 BRD-K75089421 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135082 BRD-K75089421 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135106 BRD-K75089421 HEK293 0.08 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
135203 BRD-K75089421 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135259 BRD-K75089421 MDAMB231 0.74 uM 24 h 0.26 1.08 0.22 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).