CMap Candidate Details

Structure:
CMap ID: C26357
Pert ID: BRD-K75308783
Compound Name: SAR-245409
Targets: --
MoA: --
SMILES: COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(NC(=O)c3ccc(C)c(OC)c3)cc2)cc(OC)c1
InchiKey: HJSSPYJVWLTYHG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91832 BRD-K75308783 HS578T 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.27
91851 BRD-K75308783 MCF10A 0.08 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
91884 BRD-K75308783 MCF??7.00 0.37 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91919 BRD-K75308783 MDAMB231 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91950 BRD-K75308783 SKBR3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92861 BRD-K75308783 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92919 BRD-K75308783 ASC 1.11 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
92977 BRD-K75308783 CD34 0.04 uM 24 h -0.26 -1.08 0.3 0.0 0.0 0.0
93069 BRD-K75308783 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93116 BRD-K75308783 HELA 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93204 BRD-K75308783 HUVEC 0.04 uM 24 h 0.25 1.05 0.16 0.0 0.0 0.0
93260 BRD-K75308783 JURKAT 10 uM 24 h -0.3 -1.25 0.68 0.0 0.0 0.0
93386 BRD-K75308783 NPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93437 BRD-K75308783 PC3 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93505 BRD-K75308783 SKL 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93531 BRD-K75308783 THP1 0.12 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.85
93572 BRD-K75308783 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117389 BRD-K75308783 A549 0.125 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
117431 BRD-K75308783 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117475 BRD-K75308783 HCC515 10 uM 24 h 0.34 1.4 1.03 0.0 0.0 0.0
117521 BRD-K75308783 HEPG2 0.37 uM 24 h 0.21 0.86 0.01 -0.36 -1.2 1.17
117565 BRD-K75308783 HT29 1.11 uM 24 h 0.25 1.04 0.14 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).