CMap Candidate Details

Structure:
CMap ID: C02640
Pert ID: BRD-K00766422
Compound Name: sparfosic-acid
Targets: CAD
MoA: Aspartate carbamoyltransferase inhibitor
SMILES: OC(=O)C[C@H](NC(=O)CP(O)(O)=O)C(O)=O
InchiKey: ZZKNRXZVGOYGJT-VKHMYHEASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8892 BRD-K00766422 A375 80 uM 24 h -0.24 -1.0 0.15 0.3 1.07 0.63
9160 BRD-K00766422 A549 80 uM 6 h 0.3 1.24 0.53 0.25 0.9 0.21
9326 BRD-K00766422 AGS 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9631 BRD-K00766422 H1299 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9937 BRD-K00766422 HA1E 80 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.14
10186 BRD-K00766422 HCC515 80 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10431 BRD-K00766422 HCT116 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10704 BRD-K00766422 HEPG2 80 uM 6 h 0.0 0.0 0.0 -0.34 -1.13 0.99
11089 BRD-K00766422 HT29 80 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
11192 BRD-K00766422 MCF??7.00 80 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11380 BRD-K00766422 NCIH2073 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11685 BRD-K00766422 NCIH508 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11952 BRD-K00766422 NCIH596 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12236 BRD-K00766422 NOMO1 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12507 BRD-K00766422 PC3 80 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
13179 BRD-K00766422 U937 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13560 BRD-K00766422 VCAP 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).