CMap Candidate Details

Structure:
CMap ID: C26421
Pert ID: BRD-K75532464
Compound Name: FTI-276
Targets: FNTA
MoA: Farnesyltransferase inhibitor
SMILES: CSCC[C@H](NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c1ccccc1)C(O)=O
InchiKey: ZIXDDEATQSBHHL-BEFAXECRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8980 BRD-K75532464 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9502 BRD-K75532464 AGS 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.89 0.27
9806 BRD-K75532464 H1299 10 uM 6 h -0.27 -1.13 0.4 -0.25 -0.84 0.18
10080 BRD-K75532464 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
10223 BRD-K75532464 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10589 BRD-K75532464 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10845 BRD-K75532464 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.23
11012 BRD-K75532464 HT29 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.1
11570 BRD-K75532464 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11833 BRD-K75532464 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.21 0.74 0.03
12377 BRD-K75532464 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12627 BRD-K75532464 PC3 10 uM 6 h 0.25 1.06 0.18 0.22 0.79 0.07
12863 BRD-K75532464 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13074 BRD-K75532464 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13354 BRD-K75532464 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13676 BRD-K75532464 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90533 BRD-K75532464 A549 3.33 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
90550 BRD-K75532464 MCF??7.00 0.125 uM 6 h 0.23 0.98 0.09 -0.3 -1.01 0.56
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).