CMap Candidate Details

Structure:
CMap ID: C26471
Pert ID: BRD-K75693278
Compound Name: SA-1458985
Targets: --
MoA: --
SMILES: O[C@@H]1COC[C@@H]2O[C@@H](CC(=O)NCCc3ccncc3)CC[C@H]2N(Cc2cccc(c2)C(F)(F)F)C1
InchiKey: QCHQNBIYSRQADD-KEZOAJOQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
61207 BRD-K75693278 VCAP 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
86556 BRD-K75693278 A375 10 uM 24 h 0.24 1.01 0.11 0.0 0.0 0.0
86644 BRD-K75693278 A549 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
86734 BRD-K75693278 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
86840 BRD-K75693278 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.21
86950 BRD-K75693278 HEPG2 4 uM 24 h 0.26 1.07 0.2 0.0 0.0 0.0
87055 BRD-K75693278 HT29 4 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.12
87147 BRD-K75693278 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.33 1.78
87240 BRD-K75693278 PC3 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97577 BRD-K75693278 NKDBA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
112467 BRD-K75693278 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.66
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).