CMap Candidate Details

Structure:
CMap ID: C00265
Pert ID: BRD-A10355991
Compound Name: norketamine
Targets: CYP3A4
MoA: Glutamate receptor antagonist
SMILES: NC1(CCCCC1=O)c2ccccc2Cl
InchiKey: BEQZHFIKTBVCAU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1479 BRD-A10355991 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
2027 BRD-A10355991 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2316 BRD-A10355991 PC3 10 uM 6 h -0.24 -0.99 0.14 -0.25 -0.85 0.2
2739 BRD-A10355991 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.24 1.31
41868 BRD-A10355991 A549 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
42173 BRD-A10355991 ASC 10 uM 24 h -0.19 -0.8 0.0 0.0 0.0 0.0
42518 BRD-A10355991 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42828 BRD-A10355991 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43109 BRD-A10355991 MCF??7.00 10 uM 24 h 0.24 0.98 0.09 -0.37 -1.25 1.35
43989 BRD-A10355991 SKB 10 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.59
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).