CMap Candidate Details

Structure:
CMap ID: C26640
Pert ID: BRD-K76197012
Compound Name: ulipristal
Targets: PGR
MoA: Progesterone receptor antagonist
SMILES: CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(OC(C)=O)C(C)=O)[C@@H]2CCC3=CC(=O)CCC3=C12
InchiKey: OOLLAFOLCSJHRE-ONBAZCQBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95315 BRD-K76197012 A549 10 uM 48 h 0.0 0.0 0.0 -0.32 -1.07 0.75
95393 BRD-K76197012 U2OS 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
127018 BRD-K76197012 A375 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.42
127043 BRD-K76197012 HA1E 10 uM 24 h 0.26 1.07 0.2 0.0 0.0 0.0
127099 BRD-K76197012 HELA 10 uM 24 h 0.25 1.04 0.15 -0.39 -1.33 1.71
127138 BRD-K76197012 HT29 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
127208 BRD-K76197012 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.53
127237 BRD-K76197012 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127282 BRD-K76197012 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
127313 BRD-K76197012 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135108 BRD-K76197012 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.26
135170 BRD-K76197012 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.49
135206 BRD-K76197012 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135264 BRD-K76197012 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).